Two First Nations-owned companies will have some of the best footballers in the world "on loan" to promote their businesses in a new CommBank-led advertising campaign.

Waddi Group and Jyelah Mind & Body are among 50 competition winners who will have several Matildas players in their corner as part of a nationwide ad blitz.

Jyelah Mind & Body founder Kerrilee Philp said she was inspired by her Aboriginal grandmothers' passion and belief in the power of bush medicine.

The proud Ngiyampaa and Barkindji woman said with the help of traditional Indigenous knowledge, her NSW-based business was able to produce a range of natural skincare products that treat everything from dryness, acne, and eczema to everyday grazes and blisters.

"As an Indigenous-owned, female-run small business, I'm proud to have the backing of the CommBank Matildas in amplifying my story of resilience and helping generate awareness of the restorative powers of native bush medicine," Ms Philp said.

"Jyelah Mind & Body specialises in providing a range of natural skincare products formulated with ingredients that are ethically and sustainably sourced from the Australian bush.

"With the support of the CommBank Matildas, I hope to help more Aussies achieve healthier skin and improve their self-confidence while showcasing my Indigenous culture to the world."

Waddi Group owner Tomika Johnson said her 100-percent Indigenous-owned company, which had offices in Brisbane and Perth, was committed to building brighter futures for Indigenous Australians nationwide.

The proud Gooreng Gooreng woman who started the company with her partner Cory Reeve said the business specialised in producing quality spring water and coffee to service the country's national footprint.

"Partnering with the CommBank Matildas showcases a shared commitment to resilience, teamwork and Australian pride, and together, we can inspire Australians to strive for excellence on and off the field," she said.

As a First Nations business, we're proud to showcase our passion for Indigenous excellence and contribute to this thriving business sector, leveraging CommBank's support to grow our business and reach even more Australians."

Matildas midfielder Kyra Cooney-Cross said there were many similarities between playing in a sporting team and owning a small business.

"You have to show up every day and we're both under quite a lot of pressure," Ms Cooney-Cross said.

"Slow and steady wins the race and that goes for both – it takes a lot of hard work, and it'll take time as well.